Search results for "Orf virus"
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CUTANEOUS NEOFORMATIONS ASSOCIATED WITH COINFECTION BY ORF VIRUS AND ORTHOPOXVIRUS IN GOATS IN SICILY
2014
Parapoxvirus - ORF virus (ORFV) is the etiological agent of contagious ecthyma, a severe zoonotic exanthematic disease that affects small ruminants. It is usually characterized by highly infectious pustules and papillomatous lesions on the skin of the lips, tongue, and around the mouth. In more severe cases, the skin of the eyes, feet, vulva or udder may also be affected. Orthopoxvirus has been sometimes associated with naturally spreading disease in domestic and wild animals. Parapoxvirus infection can be complicate by opportunistic agents, mainly Fusiformis necrophorus, Dermatophilus congolensis or be invaded by the larvae of flies. Little is reported on co-infection with other viruses. T…
Characterization of the immune cells response and ultrastructural study of dendritic cell Golgi Apparatus role in ORF virus infection
2014
Contagious Ecthyma is an acute skin anthropozoonosis caused by orf virus (ORFV), which affects sheep and goat. The infectious agent is an epitheliotropic, double- stranded DNA poxvirus. Infection happens via the hurt skin, and causes a localized virus production in the epidermal cells and keratinocytes. This paper characterize the cellular immune response by cytochemistry in ORFV infection and studies the role of Golgi Apparatus (GA) of keratinocytes by transmission electron microscopy (TEM) and 3D models. Twenty cutaneous biopsies in sheep from ORFV infected lesions were fixed in 10% formalin and embedded in paraffin for light microscopy. Paraffin sections were immunocytochemically stained…